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About the program

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The ICARE-Nanomed Program, funded by the Natural Sciences and Engineering Research Council of Canada (NSERC) through the Collaborative Research and Training Experience (CREATE) program, aims to train a new generation of highly qualified personnel capable of characterizing nanoparticles and evaluating their interactions with biological environments for applications in nanomedicine. This innovative program aims to build the capacity needed to address major challenges in nanoparticle commercialization, spanning nanoparticle synthesis, characterization, and preclinical experiments. Through an interdisciplinary approach, ICARE-Nanomed offers specialized coursework, interactive workshops, industrial internships, and collaborative research projects. These activities equip participants with the essential skills and tools to advance the development of safe, effective nanomedicines—including vaccines, drug delivery systems, and radiosensitizers.

Context

The COVID-19 pandemic accelerated the development and adoption of nanomedicines, with mRNA–lipid nanoparticle vaccines demonstrating their potential at an unprecedented scale and driving rapid growth in the field. At the same time, this momentum has highlighted critical gaps in Canada’s capacity to sustain and advance nanomedicine innovation. Training opportunities that integrate engineering, nanotechnology, biology, and regulatory science remain limited, while expertise in nanoparticle stability and characterization, including colloidal, physicochemical, and chemical interactions with biological fluids, remains fragmented across the country. Graduate students working on nanomedicine technologies are often exposed to only a subset of the analytical processes required to support regulatory approval, leaving a gap between academic training and the multidisciplinary expertise required in industry. Meanwhile, emerging technologies such as microfluidics, machine learning, plasmonics, and artificial intelligence remain underutilized in analytical workflows, despite their potential to enhance precision and accelerate the characterization and evaluation of new nanomedicines. ICARE-Nanomed was created to address these challenges by establishing a national, interdisciplinary training network that equips highly qualified personnel with the scientific and technical expertise, regulatory awareness, and strategic perspective needed to translate nanomedicine research into impactful innovations and strengthen Canada’s capacity in this rapidly evolving field.

Établir des procédures optimales de synthèse et de purification

Establish optimal nanomedicine synthesis and purification procedures prior to generating largescale analytical datasets for machine learning and artificial intelligence applications

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Develop deep expertise among students in analytical cascade assays methodologies, including the protocols and technologies required to generate scientific evidence supporting new nanomedicine products.

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Elucidate and integrate molecular interactions between biological fluid components (e.g. proteins, metabolites) and nanoparticle surfaces into analytical cascade assays frameworks

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Raise awareness among highly qualified personnel engaged in nanomedicine research in Canada about the translational, commercial, and regulatory dimensions of these products within the North American context

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Innovate within analytical cascade assay practices by incorporating advanced technologies such as machine learning, artificial intelligence, microfluidics, and plasmonics to enhance speed, precision, sensitivity, and efficiency

Objectives

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